Independent Bays
Independently addressable sample bays. Isolate cells or nuclei from either bay at any time.
Rapid Results
Nuclei in ~7 minutes. 8 samples complete in ~30 minutes.
Easy to Use
Get great results on day one. Robust protocols are preloaded and easily optimized for new tissue types.
Independent Bays
Independently addressable sample bays. Isolate cells or nuclei from either bay at any time.
Rapid Results
Nuclei in ~7 minutes. 8 samples complete in ~30 minutes.
Easy to Use
Get great results on day one. Robust protocols are preloaded and easily optimized for new tissue types.
Proven Technology
The Singulator 200 uses the same proven dissociation technology as our Singulator 100. Designed for ease of use, resulting in fast implementation and protocol optimization.
The system comes with preloaded, adjustable protocols, allowing you to achieve great results from day one on everything from human to honeybee, plants to planaria, and more.
Flexible Automation
The Singulator continues to be the most powerful and flexible platform in the industry and is the only fully automated platform that can isolate either cells or nuclei. Like the Singulator 100, the Singulator 200 is open and customizable. Its preloaded protocols can be easily modified for optimum results across a wide variety of tissue types. The system can accept S2 Genomics’ reagents or your own, giving you complete control over your samples and methods. The disposable sample cartridges for the Singulator 200 are backward compatible with the Singulator 100, allowing you to expand your sample capacity with no process re-optimization or additional supplies to stock.
Your samples, your expertise, your choices!
Flexible Automation
The Singulator continues to be the most powerful and flexible platform in the industry and is the only fully automated platform that can isolate either cells or nuclei. Like the Singulator 100, the Singulator 200 is open and customizable. Its preloaded protocols can be easily modified for optimum results across a wide variety of tissue types. The system can accept S2 Genomics’ reagents or your own, giving you complete control over your samples and methods. The disposable sample cartridges for the Singulator 200 are backward compatible with the Singulator 100, allowing you to expand your sample capacity with no process re-optimization or additional supplies to stock.
Your samples, your expertise, your choices!
Higher Throughput
With the Singulator 200’s independent sample bays, you can run nuclei and cell protocols simultaneously, or two nuclei or two cell protocols in parallel, providing flexibility and efficiency for laboratory operations.
The Singulator system includes instrumentation, protocols, reagents, and sample cartridges for a complete tissue dissociation solution that seamlessly integrates into your workflow.
Additional Features
Parallel Users
Two users can operate separate bays simultaneously, increasing workflow flexibility for your lab.
Space Saving Design
With an integrated reagent chiller, the Singulator 200 is only slightly larger than our Singulator 100.
Touch Screen Interface
All Singulator devices have an intuitive and easy-to-use touch-screen interface.
All Runs Logged and Recorded
As with our Singulator 100, all sample runs on the Singulator 200 are logged with associated video allowing you to ensure process control and use tracking.
See the Singulator In Action
Watch this video to learn how to prepare single-nuclei suspension from mouse kidney tissue on the Singulator platform.
Performance At A Glance
The Singulator™ 200 System comes with a unique Single-Shot Mechanism™ for convenient cell-isolation reagent loading and a Reagent Chiller that stores reagents for up to 100 nuclei isolations.
The Singulator Platform
High Yields & Viability
Typical Yield:
- 10,000 to >500,000 cells/mg*
- 20,000 to >600,000 nuclei/mg*
*tissue dependent
Reproducible Results
- Consistent results, from researcher to researcher and lab to lab
- Improve success rates for precious samples
- Minimize transcriptome changes
- Optionally, use your reagents for your specific tissues
Fast Processing
- Nuclei in 7-12 minutes
- Single cells in 20-60 minutes
Simple Setup. Walk-away Operation
- Load tissue and press RUNin < 1 minute
- Intuitive touch-screen interface
- Minimal operator training
Singulator 200 Gallery
Get Started with the Singulator 200
Interested in working or collaborating with us?
Resources
Tech Note: Comparison of Evercode™ WT v2 and Chromium™ Next GEM Single Cell 3’ Kit v3.1 in Mouse Kidney Cells
Application Note: Single Nuclei Sequencing Using the Singulator™ Platform and S2 Genomics RNase Inhibitor
Poster Download: Nuclei Isolation from Immature Embryos of Wild Sorghum purpureosericeum with the Singulator™ 100 system
Poster Download: Automated processing of solid tissues into single cells or nuclei for genomics and cell biology applications with the Singulator™ 100 and 200 systems
Poster Download: Automated processing of solid tissues into single cells or nuclei with the Singulator™ 100 system: scRNA-Seq, and ATAC-Seq data on Human and Mouse Tissues – AGBT 2022
Tech Note: Use of NIC+ with the Singulator 100 For Sub-20 mg Samples
Tech Note: Singulator™ 100 and MARS®: Efficient Nuclei Isolation from a variety of tissue samples
Tech Note: Use of RNase Inhibitor with the Singulator™ 100
Keystone 2021 Poster Download: Automated Processing of Solid Tissues into Single Cells or Nuclei for Single Cell Analysis
