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MARS® acoustic technology utilizes active-microfluidics acoustics for the separation of single cells or nuclei without labeling, based only on the difference in their physical parameters. The cells are isolated with high recovery and ready for single-cell genomics. The Singulator™ 100 System automates the processing of solid tissue samples into suspensions of single cells or nuclei with high yields and from small samples for a wide range of single-cell biology and genomic analyses.